It is important that you inform your doctor if you have a low level of platelets in your blood, kidney disease, uncontrolled active bleeding, an allergy to pork products, or cannot have accurate blood testing done prior to and during dosing.

Additionally, tell your doctor if you have bacterial endocarditis, high blood pressure that is not being controlled, eye problems due to diabetes (diabetic retinopathy), need to have surgery or another invasive procedure, hemophilia or another blood disorder, a stomach ulcer, a prosthetic heart valve, or liver disease. You may not be able to use enoxaparin, or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. Patients with an allergy to benzyl alcohol should not use the multi-dose formulation of enoxaparin.

Do not take aspirin, ibuprofen (Motrin®, Advil®, Nuprin®, and others), ketoprofen (Orudis KT®, Orudis®, Oruvail®), naproxen (Aleve®, Naprosyn®, Anaprox®, and others), indomethacin (Indocin®), or any other nonsteroidal anti-inflammatory drug (NSAID) without first talking to your doctor. These medicines may lead to bleeding when taken with enoxaparin. Ask your pharmacist or doctor before taking any prescription or over-the-counter medication during treatment with enoxaparin.

Medication other than those listed here may also interact with enoxaparin. Talk to your doctor and pharmacist before using any prescription or over-the-counter medicines, including herbal products.

Moreover, there is a risk of bleeding in the spinal or epidural space, possibly resulting in paralysis, when enoxaparin is used along with spinal or epidural anesthesia or spinal puncture. This risk may be increased by the use of indwelling epidural catheters or by the concomitant use of drugs that affect blood clotting.

Enoxaparin falls into the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use enoxaparin without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Furthermore, it is not known whether enoxaparin passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

 

FDA Information

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In case of an emergency/overdose